If you have struggled to lose weight
or keep it off, your hormones may be at play, according to a recent study.
The Mayo Clinic-led study found that obese teenagers have lower levels of a
hormone potentially tied to weight management than teens of normal weights.
Seema Kumar, one of the study's authors, said that the study is the first to
look at levels of spexin in the pediatric population, adding "Previous
research has found reduced levels of this hormone in adults with obesity."Overall, our findings suggest spexin may play a role in weight gain,
beginning at an early age."
The cross-sectional study analyzed spexin levels in 51 obese and 18 teenagers
of normal weights between ages 12 and 18.
The participants had blood samples
taken between 2008 and 2010 as part of separate clinical trials.
"It is noteworthy that we see such clear differences in spexin levels
between obese and normal weight adolescents," Kumar noted.
"Since this is a cross-sectional study, more research is needed to explore
the physiological significance of spexin, how it may be involved in the
development of childhood obesity, and whether it can be used to treat or manage
the condition."
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